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1

Second Myeloid Malignancies in a Large Cohort of Patients With Chronic Lymphocytic Leukemia: A Single Institution Experience

Chavez, Julio C., Dalia, Samir, Sandoval-Sus, Jose, Kharfan-Dabaja, Mohamed A., Al-Ali, Najla, Komrokji, Rami, Padron, Eric, Corrales-Yepez, Gabriela, Rock-Klotz, Jennifer, Pinilla-Ibarz, Javier

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2015

Language:

english

File:

PDF, 278 KB

english, 2015

2

Overall survival with ponatinib versus allogeneic stem cell transplantation in Philadelphia chromosome-positive leukemias with the T315I mutation

Nicolini, Franck E., Basak, Grzegorz W., Kim, Dong-Wook, Olavarria, Eduardo, Pinilla-Ibarz, Javier, Apperley, Jane F., Hughes, Timothy, Niederwieser, Dietger, Mauro, Michael J., Chuah, Charles, Hochha

Journal:

Year:

2017

Language:

english

File:

PDF, 209 KB

english, 2017

3

Design and rationale for the life after stopping tyrosine kinase inhibitors (LAST) study, a prospective, single-group longitudinal study in patients with chronic myeloid leukemia

Atallah, Ehab, Schiffer, Charles A., Weinfurt, Kevin P., Zhang, Mei-Jie, Radich, Jerald P., Oehler, Vivian G., Pinilla-Ibarz, Javier, Deininger, Michael W. N., Lin, Li, Larson, Richard A., Mauro, Mich

Journal:

Year:

2018

Language:

english

File:

PDF, 376 KB

english, 2018

4

Incidence and Management of Venous Thrombo-Embolism (VTE) Associated with CD19-Directed Chimeric Antigen Receptor (CAR) T-Cell Therapy: A Single Institution Experience

Hashmi, Hamza, Mirza, Abu-Sayeef, Darwin, Alicia, Logothetis, Constantine, Garcia, Franco, Kommalapati, Anuhya, Bachmeier, Christina A., Chavez, Julio C., Shah, Bijal D., Pinilla-Ibarz, Javier, Khiman

Journal:

Biology of Blood and Marrow Transplantation

Year:

2020

File:

PDF, 55 KB

2020

5

Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial

Al-Sawaf, Othman, Zhang, Can, Tandon, Maneesh, Sinha, Arijit, Fink, Anna-Maria, Robrecht, Sandra, Samoylova, Olga, Liberati, Anna M, Pinilla-Ibarz, Javier, Opat, Stephen, Sivcheva, Liliya, Le DÃ», Kat

Journal:

The Lancet Oncology

Year:

2020

File:

PDF, 60 KB

2020

6

Clinical and therapeutic implications of the mutational status of IgVH in patients with chronic lymphocytic leukemia

Mohamed A. Kharfan-Dabaja, Julio C. Chavez, Khadija A. Khorfan, Javier Pinilla-Ibarz

Journal:

Year:

2008

Language:

english

File:

PDF, 119 KB

english, 2008

7

Phase 1 study of INNO-406, a dual Abl/Lyn kinase inhibitor, in Philadelphia chromosome-positive leukemias after imatinib resistance or intolerance

Hagop Kantarjian, Phillipp le Coutre, Jorge Cortes, Javier Pinilla-Ibarz, Arnon Nagler, Andreas Hochhaus, Shinya Kimura, Oliver Ottmann

Journal:

Year:

2010

Language:

english

File:

PDF, 226 KB

english, 2010

8

Intolerance to tyrosine kinase inhibitors in chronic myeloid leukemia : Definitions and clinical implications

Javier Pinilla-Ibarz, Jorge Cortes, Michael J. Mauro

Journal:

Year:

2011

Language:

english

File:

PDF, 168 KB

english, 2011

9

Enhanced CD8 T cell cross-presentation by macrophages with targeted disruption of STAT3

Jason Brayer, Fengdong Cheng, Hongwei Wang, Pedro Horna, Ildefonso Vicente-Suarez, Javier Pinilla-Ibarz, Eduardo M. Sotomayor

Journal:

Immunology Letters

Year:

2010

Language:

english

File:

PDF, 465 KB

english, 2010

10

Peptide binding motif predictive algorithms correspond with experimental binding of leukemia vaccine candidate peptides to HLA-A*0201 molecules

Marta Gomez-Nunez, Javier Pinilla-Ibarz, Tao Dao, Rena J. May, Mary Pao, Jaspreet S. Jaggi, David A. Scheinberg

Journal:

Leukemia Research

Year:

2006

Language:

english

File:

PDF, 107 KB

english, 2006

11

Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers

Jason A. Dubovsky, Daniel Wang, John J. Powers, Emmanuel Berchmans, Matthew A. Smith, Kenneth L. Wright, Eduardo M. Sotomayor, Javier A. Pinilla-Ibarz

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 1.98 MB

english, 2011

12

Salvage chemotherapy regimens for acute myeloid leukemia: Is one better? Efficacy comparison between CLAG and MEC regimens

Samantha L. Price, Jeffrey E. Lancet, Timothy J. George, Gene A. Wetzstein, Alan F. List, Viet Q. Ho, Hugo F. Fernandez, Javier Pinilla-Ibarz, Mohamed A. Kharfan-Dabaja, Rami S. Komrokji

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 414 KB

english, 2011

13

A database of reaction monitoring mass spectrometry assays for elucidating therapeutic response in cancer

Elizabeth R. Remily-Wood, Richard Z. Liu, Yun Xiang, Yi Chen, C. Eric Thomas, Neal Rajyaguru, Laura M. Kaufman, Joana E. Ochoa, Lori Hazlehurst, Javier Pinilla-Ibarz, Jeffrey Lancet, Guolin Zhang, Eri

Journal:

PROTEOMICS - Clinical Applications

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

14

Modern approaches to treating chronic myelogenous leukemia

Javier Pinilla-Ibarz, Celeste Bello

Journal:

Current Oncology Reports

Year:

2008

Language:

english

File:

PDF, 245 KB

english, 2008

15

A pilot vaccination trial of synthetic analog peptides derived from the BCR-ABL breakpoints in CML patients with minimal disease

Maslak, P G, Dao, T, Gomez, M, Chanel, S, Packin, J, Korontsvit, T, Zakhaleva, V, Pinilla-Ibarz, J, Berman, E, Scheinberg, D A

Journal:

Year:

2008

Language:

english

File:

PDF, 202 KB

english, 2008

16

Improved human T-cell responses against synthetic HLA-0201 analog peptides derived from the WT1 oncoprotein

Pinilla-Ibarz, J, May, R J, Korontsvit, T, Gomez, M, Kappel, B, Zakhaleva, V, Zhang, R H, Scheinberg, D A

Journal:

Year:

2006

Language:

english

File:

PDF, 222 KB

english, 2006

17

CML vaccines as a paradigm of the specific immunotherapy of cancer

J. Pinilla-Ibarz, K. Cathcart, D.A. Scheinberg

Journal:

Year:

2000

Language:

english

File:

PDF, 100 KB

english, 2000

18

Hypoalbuminemia is an independent prognostic factor for overall survival in myelodysplastic syndromes

Rami S. Komrokji, Maria Corrales-Yepez, Mohamed A. Kharfan-Dabaja, Najla H. Al Ali, Eric Padron, Dana E. Rollison, Javier Pinilla-Ibarz, Ling Zhang, Pearlie K. Epling-Burnette, Jeffrey E. Lancet, Alan

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 162 KB

english, 2012

19

A case of acute basophilic leukemia arising from chronic myelogenous leukemia with development of t(7;8)(q32;q13)

Joseph Pidala, Javier Pinilla-Ibarz, Hernani D. Cualing

Journal:

Cancer Genetics and Cytogenetics

Year:

2008

Language:

english

File:

PDF, 502 KB

english, 2008

20

Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2′-deoxycytidine

Jason A. Dubovsky, John J. Powers, Yang Gao, Luis F. Mariusso, Eduardo M. Sotomayor, Javier A. Pinilla-Ibarz

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 1.16 MB

english, 2011

21

Potentiation of Nilotinib-mediated cell death in the context of the bone marrow microenvironment requires a promiscuous JAK inhibitor in CML

Rajesh R. Nair, Joel H. Tolentino, Raul F. Argilagos, Ling Zhang, Javier Pinilla-Ibarz, Lori A. Hazlehurst

Journal:

Leukemia Research

Year:

2012

Language:

english

File:

PDF, 753 KB

english, 2012

22

Selective depletion of T cell clones responsible for GVHD in a murine model

B.J. Kappel, J.M. Eng, J. Pinilla-Ibarz, M.M.R.M. van den Brink, D.A. Scheinberg

Journal:

Biology of Blood and Marrow Transplantation

Year:

2004

Language:

english

File:

PDF, 73 KB

english, 2004

23

A Novel Reduced Toxicity Preparative Regimen For Hematopoietic Cell Allografting Combining Pentostatin (Nipent®) And Targeted Doses Of Intravenous Busulfan (Busulfex®) With Or Without Rituximab (PB ± R) Using CD4-Guided Immune Suppression: Preliminary Results Of An Ongoing Prospective Trial

M.A. Kharfan-Dabaja, J. Perkins, R. Cortes, L. Brand, H.F. Fernandez, J.L. Ochoa-Bayona, T. Field, L. Perez, C. McIsaac, B. Maddox, E. Ayala, R. Komrokji, J. Pinilla-Ibarz, E. Sotomayor, M. Tomblyn, C

Journal:

Biology of Blood and Marrow Transplantation

Year:

2010

Language:

english

File:

PDF, 56 KB

english, 2010

24

Novel targeted and immunotherapeutic strategies in chronic myeloid leukemia

Joseph Schwartz, Javier Pinilla-Ibarz, Rui Rong Yuan, David A. Scheinberg

Journal:

Seminars in Hematology

Year:

2003

Language:

english

File:

PDF, 108 KB

english, 2003

25

A molecular and functional analysis of large granular lymphocyte expansions in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitors

Powers, John J., Dubovsky, Jason A., Epling-Burnette, P. K., Moscinski, Lynn, Zhang, Ling, Mustjoki, Satu, Sotomayor, Eduardo M., Pinilla-Ibarz, Javier A.

Journal:

Leukemia and Lymphoma

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

26

Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study

Giles, F J, le Coutre, P D, Pinilla-Ibarz, J, Larson, R A, Gattermann, N, Ottmann, O G, Hochhaus, A, Radich, J P, Saglio, G, Hughes, T P, Martinelli, G, Kim, D-W, Novick, S, Gillis, K, Fan, X, Cortes,

Journal:

Year:

2013

Language:

english

File:

PDF, 383 KB

english, 2013

27

Outcome of Diffuse Large B-Cell Lymphoma in the United States Has Improved Over Time but Racial Disparities Remain: Review of SEER Data

Rami S. Komrokji, Najla H. Al Ali, M.S. Beg, Malek M. Safa, Dana Rollison, Mohamed Kharfan-Dabaja, Celeste Bello, Jennifer Cultrera, Lubomir Sokol, Javier Pinilla-Ibarz, Eduardo M. Sotomayor

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2011

Language:

english

File:

PDF, 419 KB

english, 2011

28

The expanding options for front-line treatment in patients with newly diagnosed CML

Javier Pinilla-Ibarz, Ian Flinn

Journal:

Critical Reviews in Oncology/Hematology

Year:

2012

Language:

english

File:

PDF, 201 KB

english, 2012

29

Prediction of outcomes in patients with Ph+ chronic myeloid leukemia in chronic phase treated with nilotinib after imatinib resistance/intolerance

Jabbour, E, le Coutre, P D, Cortes, J, Giles, F, Bhalla, K N, Pinilla-Ibarz, J, Larson, R A, Gattermann, N, Ottmann, O G, Hochhaus, A, Hughes, T P, Saglio, G, Radich, J P, Kim, D-W, Martinelli, G, Rey

Journal:

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

30

Quality of life outcomes in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors: a controlled comparison

Phillips, Kristin M., Pinilla-Ibarz, Javier, Sotomayor, Eduardo, Lee, Morgan R., Jim, Heather S. L., Small, Brent J., Sokol, Lubomir, Lancet, Jeffrey, Tinsley, Sara, Sweet, Kendra, Komrokji, Rami, Jac

Journal:

Supportive Care in Cancer

Year:

2013

Language:

english

File:

PDF, 152 KB

english, 2013

31

Validation of the revised International Prognostic Scoring System in treated patients with myelodysplastic syndromes

Mishra, Asmita, Corrales-Yepez, Maria, Ali, Najla Al, Kharfan-Dabaja, Mohamed, Padron, Eric, Zhang, Ling, Epling-Burnette, Pearlie K., Pinilla-Ibarz, Javier, Lancet, Jeffrey E., List, Alan F., Komrokj

Journal:

American Journal of Hematology

Year:

2013

Language:

english

File:

PDF, 174 KB

english, 2013

32

Biomarkers for determining the prognosis in chronic myelogenous leukemia

Kendra Sweet, Ling Zhang, Javier Pinilla-Ibarz

Journal:

Journal of Hematology & Oncology

Year:

2013

Language:

english

File:

PDF, 247 KB

english, 2013

33

Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells

Cheng, Fengdong, Lienlaf, Maritza, Perez-Villarroel, Patricio, Wang, Hong-Wei, Lee, Calvin, Woan, Karrune, Woods, David, Knox, Tessa, Bergman, Joel, Pinilla-Ibarz, Javier, Kozikowski, Alan, Seto, Edwa

Journal:

Molecular Immunology

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

34

Genomic aberrations deletion 11q and deletion 17p independently predict for worse progression-free and overall survival after allogeneic hematopoietic cell transplantation for chronic lymphocytic leukemia

Chavez, Julio C., Kharfan-Dabaja, Mohamed A., Kim, Jongphil, Yue, Binglin, Dalia, Samir, Pinilla-Ibarz, Javier, Anasetti, Claudio, Locke, Frederick L.

Journal:

Leukemia Research

Year:

2014

Language:

english

File:

PDF, 331 KB

english, 2014

35

P-100 Validation of the Revised International Prognostic Scoring System (IPSS-R) and its therapeutic implications

Mishra, A., Corrales-Yepez, M., Al-Ali, N., Kharfan-Dabaja, M., Padron, E., Zhang, L., Epling-Burnette, P., Pinilla-Ibarz, J., Lancet, J.E., List, A.F., Komrokji, R.S.

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 744 KB

english, 2013

36

The one-two punch: Combination treatment in chronic myeloid leukemia

Sweet, Kendra L., Hazlehurst, Lori A., Pinilla-Ibarz, Javier

Journal:

Critical Reviews in Oncology/Hematology

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

37

776: Inhibition of the IRE-1/XBP-1 pathway synergizes with ibrutinib for the treatment of B cell cancer

Tang, C.H., Ranatunga, S., Kriss, C., Cubitt, C., Tao, J., Pinilla-Ibarz, J., Del Valle, J., Hu, C.C.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 81 KB

english, 2014

38

Increased genomic instability may contribute to the development of kinase domain mutations in chronic myeloid leukemia

Sweet, Kendra, Al Ali, Najla H., Dalia, Samir M., Komrokji, Rami S., Crescentini, Robert M., Tinsley, Sara, Lancet, Jeffrey E., Papenhausen, Peter R., Zhang, Ling, Pinilla-Ibarz, Javier

Journal:

International Journal of Hematology

Year:

2014

Language:

english

File:

PDF, 330 KB

english, 2014

39

A Novel Role for Histone Deacetylase 6 in the Regulation of the Tolerogenic STAT3/IL-10 Pathway in APCs

Cheng, F., Lienlaf, M., Wang, H.-W., Perez-Villarroel, P., Lee, C., Woan, K., Rock-Klotz, J., Sahakian, E., Woods, D., Pinilla-Ibarz, J., Kalin, J., Tao, J., Hancock, W., Kozikowski, A., Seto, E., Vil

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

40

A Phase 2 Trial of Ponatinib in Philadelphia Chromosome–Positive Leukemias

Cortes, J.E., Kim, D.-W., Pinilla-Ibarz, J., le Coutre, P., Paquette, R., Chuah, C., Nicolini, F.E., Apperley, J.F., Khoury, H.J., Talpaz, M., DiPersio, J., DeAngelo, D.J., Abruzzese, E., Rea, D., Bac

Journal:

New England Journal of Medicine

Year:

2013

Language:

english

File:

PDF, 574 KB

english, 2013

41

Circumventing Immune Tolerance Through Epigenetic Modification

Dubovsky, Jason, Villagra, Alejandro, Powers, John, Wang, Hong-Wei, Pinilla-Ibarz, Javier, Sotomayor, Eduardo

Journal:

Current Pharmaceutical Design

Year:

2010

Language:

english

File:

PDF, 204 KB

english, 2010

42

Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10

Wang, H., Cheng, F., Woan, K., Sahakian, E., Merino, O., Rock-Klotz, J., Vicente-Suarez, I., Pinilla-Ibarz, J., Wright, K. L., Seto, E., Bhalla, K., Villagra, A., Sotomayor, E. M.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.16 MB

english, 2011

43

Treatment of Chronic Lymphocytic Leukemia with a Hypomethylating Agent Induces Expression of NXF2, an Immunogenic Cancer Testis Antigen

Dubovsky, J. A., McNeel, D. G., Powers, J. J., Gordon, J., Sotomayor, E. M., Pinilla-Ibarz, J. A.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 521 KB

english, 2009

44

Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance

Bewry, N. N., Nair, R. R., Emmons, M. F., Boulware, D., Pinilla-Ibarz, J., Hazlehurst, L. A.

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 366 KB

english, 2008

45

WT1 vaccination in AML and MDS: A pilot trial with synthetic analog peptides

Brayer, Jason, Lancet, Jeffrey E., Powers, John, List, Alan, Balducci, Lodovico, Komrokji, Rami, Pinilla-Ibarz, Javier

Journal:

American Journal of Hematology

Year:

2015

Language:

english

File:

PDF, 922 KB

english, 2015

46

An update on current and prospective immunotherapies for chronic lymphocytic leukemia

Emole, Josephine N, Locke, Frederick L, Pinilla-Ibarz, Javier

Journal:

Year:

2015

Language:

english

File:

PDF, 1.48 MB

english, 2015

47

Stat3 Inhibition Augments the Immunogenicity of B-cell Lymphoma Cells, Leading to Effective Antitumor Immunity

Cheng, F., Wang, H., Horna, P., Wang, Z., Shah, B., Sahakian, E., Woan, K. V., Villagra, A., Pinilla-Ibarz, J., Sebti, S., Smith, M., Tao, J., Sotomayor, E. M.

Journal:

Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

48

Peptide Epitopes from the Wilms' Tumor 1 Oncoprotein Stimulate CD4+ and CD8+ T Cells That Recognize and Kill Human Malignant Mesothelioma Tumor Cells

May, R. J., Dao, T., Pinilla-Ibarz, J., Korontsvit, T., Zakhaleva, V., Zhang, R. H., Maslak, P., Scheinberg, D. A.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 434 KB

english, 2007

49

Molecular Action of Lenalidomide in Lymphocytes and Hematologic Malignancies

McDaniel, Jessica M., Pinilla-Ibarz, Javier, Epling-Burnette, P. K.

Journal:

Advances in Hematology

Year:

2012

Language:

english

File:

PDF, 321 KB

english, 2012

50

A Close Association of Autoimmune-Mediated Processes and Autoimmune Disorders with Chronic Myelomonocytic Leukemia: Observation from a Single Institution

Peker, Deniz, Padron, Eric, Bennett, John M., Zhang, Xiaohui, Horna, Pedro, Epling-Burnette, Pearlie K., Lancet, Jeffrey E., Pinilla-Ibarz, Javier, Moscinski, Lynn, List, Alan F., Komrokji, Rami S., Z

Journal:

Acta Haematologica

Year:

2015

Language:

english

File:

PDF, 131 KB

english, 2015

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